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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDIA3 All Species: 42.12
Human Site: T141 Identified Species: 57.92
UniProt: P30101 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30101 NP_005304.3 505 56782 T141 P A S V P L R T E E E F K K F
Chimpanzee Pan troglodytes XP_001159528 485 54945 T121 P A S V P L R T E E E F K K F
Rhesus Macaque Macaca mulatta XP_001108948 480 54081 T116 P A S V P L R T E E E F K K F
Dog Lupus familis XP_535453 687 75990 T323 P A S V P L R T E E E F E K F
Cat Felis silvestris
Mouse Mus musculus P27773 505 56660 T141 P A S V P L R T E E E F K K F
Rat Rattus norvegicus P11598 505 56605 T141 P A S V P L R T E D E F K K F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517928 483 54617 S118 P A S I P L H S D D E F E K F
Chicken Gallus gallus Q8JG64 505 56163 S139 P A S V A L S S V A D F E K F
Frog Xenopus laevis NP_001080051 502 56103 S137 P A S V D L R S V E E F E K F
Zebra Danio Brachydanio rerio NP_998070 488 54656 K133 P S S V A L L K E A D L D G F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54399 496 55763 V143 P A K D L T S V A D A E Q F L
Honey Bee Apis mellifera XP_623282 490 55838 E138 P A S K E L N E E N C L K S F
Nematode Worm Caenorhab. elegans P34329 618 69779 L263 A A K K L P K L K D V E R F M
Sea Urchin Strong. purpuratus XP_782981 472 51996 T132 P K S V V I A T E A Q F D D F
Poplar Tree Populus trichocarpa
Maize Zea mays P52588 513 57078 S153 P A S K E I K S P E D A T A L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SRG3 508 56346 S148 P A S V E I K S A D S A T E V
Baker's Yeast Sacchar. cerevisiae P17967 522 58209 V146 S Q P A V A V V A D L P A Y L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91 94.4 70.8 N.A. 93 92.2 N.A. 84.7 80.9 74.6 60 N.A. 32.6 49.5 36.7 50.5
Protein Similarity: 100 92.6 94.8 72.1 N.A. 97 96.2 N.A. 90.3 90.8 88.3 77.2 N.A. 53.4 63.7 50.4 65.9
P-Site Identity: 100 100 100 93.3 N.A. 100 93.3 N.A. 60 53.3 73.3 40 N.A. 13.3 46.6 6.6 46.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 93.3 73.3 86.6 53.3 N.A. 26.6 46.6 33.3 60
Percent
Protein Identity: N.A. 34.3 N.A. 35.6 26.8 N.A.
Protein Similarity: N.A. 51 N.A. 54.9 48.4 N.A.
P-Site Identity: N.A. 26.6 N.A. 26.6 0 N.A.
P-Site Similarity: N.A. 53.3 N.A. 60 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 83 0 6 12 6 6 0 18 18 6 12 6 6 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 % C
% Asp: 0 0 0 6 6 0 0 0 6 36 18 0 12 6 0 % D
% Glu: 0 0 0 0 18 0 0 6 53 42 48 12 24 6 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 59 0 12 71 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 6 0 % G
% His: 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 6 0 18 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 6 12 18 0 0 18 6 6 0 0 0 36 53 0 % K
% Leu: 0 0 0 0 12 65 6 6 0 0 6 12 0 0 18 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 % M
% Asn: 0 0 0 0 0 0 6 0 0 6 0 0 0 0 0 % N
% Pro: 89 0 6 0 42 6 0 0 6 0 0 6 0 0 0 % P
% Gln: 0 6 0 0 0 0 0 0 0 0 6 0 6 0 0 % Q
% Arg: 0 0 0 0 0 0 42 0 0 0 0 0 6 0 0 % R
% Ser: 6 6 83 0 0 0 12 30 0 0 6 0 0 6 0 % S
% Thr: 0 0 0 0 0 6 0 42 0 0 0 0 12 0 0 % T
% Val: 0 0 0 65 12 0 6 12 12 0 6 0 0 0 6 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 6 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _